################################################################
Dataset Information
################################################################

Dataset Name:
iPSC (Exp 1) - ALS, SMA and Control (unaffected) subject-derived iPSC lines- ATAC-seq

Dataset Description:
ATAC-Seq was carried out on isolated nuclei obtained from induced Pluripotnent Stem Cells (iPSC) cell lines.  These lines were derived from  ALS, SMA and Control (unaffected) individuals (three of each).

--Data Files in Package:
diffSites_ALS_CTR_v2.bed
diffSites_ALS_SMA_v2.bed
diffSites_SMA_CTR_v2.bed

--Metadata Files In Package:
ATAC-seq iPSC Sample Experimental Metadata_20160911.xlsx
iPSC_Metadata.txt

################################################################
Center-specific Information
################################################################

Center-specific Name:
NeuroLINCS

Center-specific Dataset ID:
LDS-1549

Center-specific Dataset Link:


################################################################
Assay Information
################################################################

Assay Overview:
Epigenomic profiles using nuclei isolated from cryopreserved cultures of iPCS cells derived from amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and control (unaffected) subjects.The ATAC-seq technique detects open-chromatin regions and maps transcription factor binding events genome-wide by means of directin vitrotransposition of native chromatin.

Date Updated:

Date Retrieved from Center:

################################################################
Metadata Information
################################################################

Metadata information regarding the entities used in the experiments is included in the accompanied metadata. A metadata file per entity category is included in the package. For example, the metadata for all the cell lines that were used in the dataset are included in the Cell_Lines_Metadata.txt file.
Descriptions for each metadata field can be found here: http://www.lincsproject.org/data/data-standards/
